1α,25‐Dihydroxy vitamin D3, the active form of vitamin D3, protects against allergeninduced airway constriction
نویسندگان
چکیده
منابع مشابه
Identification of 1,25-dihydroxycholecalciferol, a form of vitamin D3 metabolically active in the intestine.
A biologically active vitamin D(3) metabolite ("peak V metabolite") more polar than 25-hydroxycholecalciferol has been isolated from chicken intestines in pure form as a mono(trimethylsilyl)ether derivative. The molecule has been identified as 1,25-dihydroxycholecalciferol by means of mass spectrometry, ultraviolet absorption spectrophotometry, and specific chemical reactions.
متن کاملVitamin D3 and brain development.
Evidence for the presence of the vitamin D receptor in brain implies this vitamin may have some function in this organ. This study investigates whether vitamin D(3) acts during brain development. We demonstrate that rats born to vitamin D(3)-deficient mothers had profound alterations in the brain at birth. The cortex was longer but not wider, the lateral ventricles were enlarged, the cortex was...
متن کاملSpecific binding protein for active metabolites of vitamin D3.
FIG. 1 Separation of the specific protein binding with vitamin D3 and its metabolites in rat intes tinal cytoplasm by gel filtration on Sephadex G 200 after the administration of vitamin D3-3H in vivo. 1,000I.U. (3•~105cpm) of randomly labeled vitamin D3 (sp. act. 1.2•~104cpm/ug) was injected intracar dially to vitamin D deficient rat 16 hours before decapitation. 2.0 ml of rat intestinal cytop...
متن کامل25-Hydroxylation of vitamin D3: relation to circulating vitamin D3 under various input conditions.
BACKGROUND Neither the efficiency of the 25-hydroxylation of vitamin D nor the steady state relation between vitamin D(3) and 25-hydroxyvitamin D [25(OH)D] has been studied in humans. OBJECTIVE We aimed to examine the relation between serum vitamin D(3) and 25(OH)D in normal subjects after either oral administration of vitamin D(3) or ultraviolet-B radiation across a broad range of inputs. ...
متن کاملVitamin D3 intoxication induced secondary Hypertension
Background: The effects of vitamin D in skeletal system, biological metabolism and immune system function are well shown. Cholecalciferol (vitamin D3) and ergocalciferol (vitamin D2) are two major types of vitamin D. Vitamin D deficiency is widely in human population and vitamin D intoxication is very rare. Case Description: The patient is 37-years old bodybuilder man who referred to emergency...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2019
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.2019.33.1_supplement.681.2